The coverage of a base pair in a sequencing run is the number of times that it was sequenced. We usually estimate coverage in an intuitive way: by comparing the total amount of measurement to the total amount of stuff to be measured. Dividing the total length of the reads
You know a technology has made it when it shows up in a print page of Nature. So we were pleased to see that Vol. 495, Issue 293, released today, includes a piece on the rise of cloud-based next-generation sequence (NGS) analysis. The past year of conferences has given us
A flurry of papers in May of 2008 introduced the world to RNA-Seq. This new technology provided a higher resolution picture of transcription than was possible ever before. Nearly five years on, we look back at the publications that upset the microarray industry and sent tweed-clad professors scrambling for the
It is official: we are in the semi-finals. With competitors ranging from business applications to gaming to big data and high-performance computing, we are proud to be among such great company!
We will be in San Francisco for the annual meeting of the American Society for Human Genetics next week, Nov. 6 – 10. Stop by our booth 1204, say hello, and pick up a copy of our latest pipeline comparisons for exome variant calling. See you in San Francisco!
There are too many stories to relate from Beyond the Genome 2012, held at Harvard’s New Research Building last week. Many of them are beautifully synthesized in Isaac Kohane’s notes from the meeting (start here and press “Prev” to view talk notes in order). Instead of re-hashing well told tales, I will
We’re in San Francisco for the Ion World 2012 conference. Stop by and say hello! We are also presenting a poster – a Seven Bridges Genomics technical report, comparing variant calling pipelines, as you can see in the image above!
Update Feb 19, 2014: Our original Hermes uploader is now obsolete and has been replaced by a new plugin for Torrent Suite 4.x, Seven Bridges for Ion v2.0. To download the new plugin and updated user documentation, please visit our Ion homepage at www.sbgenomics.com/ion. Seven Bridges for Ion v2.0 will
This guy is awesome. He’s coding 3-dimensional shapes with DNA. And substantiates my claim that coding is magic.
John Sheffield explains how the open sharing of data is the next step in the genomics revolution. About John : John Sheffield is co-founder and president of Seven Bridges Genomics, which aims to harness open-source innovation to make genomics analysis accessible, repeatable, and sharable across the scientific community. John began