Genomics April 22nd, 2020 Assessing State of the Art Bioinformatics The Oxford English Dictionary defines bioinformatics as “the science of information and information flow in biological systems, especially of the use of computational methods in genetics and genomics.” In common vernacular, it is often defined as the use of statistical and computing methods to solve or better understand complex biological … Written by Vladimir Kovacevic Platform February 18th, 2020 Be Cloud-Agnostic: A Solution for Computing on Genomics Datasets in Distributed Cloud Locations The Multi-Cloud features on the Seven Bridges Platform allow you to work in a “cloud-agnostic” manner, enabling researchers to access and compute on datasets stored on multiple cloud locations to save time and money. Empower your research with relevant datasets regardless of where the data lives Starting a research project with data distributed in multi-cloud […] Written by Daniel Ventre Cancer Genomics Cloud December 19th, 2019 Enabling Workflow Reproducibility in the Cloud with New Pipelines from the Genomic Data Commons When analyzing genomic data, there is a vast range of bioinformatics tools and workflows to choose from. However, making an informed selection from so many options can be overwhelming, even within a relatively narrow topic, such as harmonization to a reference genome. One approach to selecting the right tool for … Written by Manisha Ray Cancer Genomics Cloud December 11th, 2019 Bioinformatics Workflow Portability is Critical to Achieving Reproducibility With the explosion of genomic data in recent years, the number of bioinformatics workflows has seen a corresponding proliferation. Researchers and developers now have a wealth of analysis options, from building their own tools to taking advantage of those developed by others. However, a workflow developed in one environment may … Written by Manisha Ray Memoization May 8th, 2019 How Memoization Enhances Efficiency for Large Scale Genomic Analysis Research Projects Memoization for large scale genomic analysis allows researchers and bioinformaticians to restart from a point of failure by enabling the reuse of existing outputs. This functionality is of critical importance given the size and complexity of genomic data and the impact of a failure on workflow efficiency and overall cost. … Written by The Seven Bridges Computation Team Automation May 1st, 2019 How Computational Workflows for Genomic Analysis can be Simplified Computational workflows are often not just computational workflows. Most interface with Library Information Management Systems (LIMS), Next-generation Sequencing (NGS) instruments, perform complex input validations, and coordinate processing between on-prem and cloud services. Many developers find that writing the code and software required to perform these integrations to be a daunting … Written by Kaushik Ghose Genomics March 8th, 2019 BioCompute and Its Importance in Accelerating Market Access for New Drugs The prevalence of NGS data within regulatory submissions has skyrocketed over the past few years which has prompted a collaboration amongst the Food and Drug Administration (FDA) and George Washington University to develop the BioCompute Object (BCO) as a standard for communicating NGS data. The BioCompute Object community aims to … Written by Dennis Dean Science March 6th, 2019 Neoantigen Discovery Using Next-Generation Sequencing Data Update (5/26/20) – Since originally publishing this post we’ve hosted a webinar on our Neoantigen Workflow. If you’d like an even deeper look at how to harness your NGS data, just click here! Leveraging neoantigens for guided treatment has become the definition of personalized cancer immunotherapy. Given their potential to … Written by Vladimir Kovacevic Useful Data February 14th, 2019 Biomedical Datasets for Large Scale Analysis Biomedical data is growing at astonishing rates with the broadening of access to next-generation sequencing (NGS) and single-cell solutions. Not only is more data being generated, but it is also being generated with improvements in base-calling accuracy, read length and the generation of reads from each end of the library … Written by Manisha Ray Posts navigation 1 2 3 4 5 6 7 … 14
