We blog about genomics. We also make a platform for open-source analysis of next generation data in the cloud. Hello.

Visualizing exome coverage depth

The coverage of a base pair in a sequencing run is the number of times that it was sequenced. We usually estimate coverage in an intuitive way: by comparing the total amount of measurement to the total amount of stuff to be measured. Dividing the total length of the reads …

Written by Nate

Cloud-based NGS analysis makes it to Nature

You know a technology has made it when it shows up in a print page of Nature. So we were pleased to see that Vol. 495, Issue 293, released today, includes a piece on the rise of cloud-based next-generation sequence (NGS) analysis. The past year of conferences has given us …

Written by Kate Blair

RNA-Seq: The first wave of papers

A flurry of papers in May of 2008 introduced the world to RNA-Seq. This new technology provided a higher resolution picture of transcription than was possible ever before. Nearly five years on, we look back at the publications that upset the microarray industry and sent tweed-clad professors scrambling for the …

Written by Kate Blair

AWS Global Start-Up Challenge Semi Finals

It is official: we are in the semi-finals. With competitors ranging from business applications to gaming to big data and high-performance computing, we are proud to be among such great company!

Written by Nate

American Society for Human Genetics 2012

We will be in San Francisco for the annual meeting of the American Society for Human Genetics next week, Nov. 6 – 10. Stop by our booth 1204, say hello, and pick up a copy of our latest pipeline comparisons for exome variant calling. See you in San Francisco!

Written by Nate

Beyond the Genome to the Clinic

There are too many stories to relate from Beyond the Genome 2012, held at Harvard’s New Research Building last week. Many of them are beautifully synthesized in Isaac Kohane’s notes from the meeting (start here and press “Prev” to view talk notes in order). Instead of re-hashing well told tales, I will …

Written by Kate Blair

Join us at Ion World 2012

We’re in San Francisco for the Ion World 2012 conference. Stop by and say hello!  We are also presenting a poster – a Seven Bridges Genomics technical report, comparing variant calling pipelines, as you can see in the image above!

Written by Nate

SBG Goes Ion Torrent

Update Feb 19, 2014: Our original Hermes uploader is now obsolete and has been replaced by a new plugin for Torrent Suite 4.x, Seven Bridges for Ion v2.0. To download the new plugin and updated user documentation, please visit our Ion homepage at Seven Bridges for Ion v2.0 will …

Written by zoran

Coding with DNA

This guy is awesome. He’s coding 3-dimensional shapes with DNA. And substantiates my claim that coding is magic.

Written by Kate Blair

We are always engaged in research and development, working to build the future of genomics, science, and health. Let's work together. We'd love to hear about your projects and challenges, so drop us a line. get in touch