Seven Bridges has the deep scientific and computing expertise to tackle uniquely complex problems in bioinformatics. We work with national initiatives to accelerate population-scale genomic research and are the only company to provide bioinformatics services to the UK and US governments.
Case study: Seven Bridges and Intel demonstrated 41% improved performance of a whole genome analysis
Seven Bridges’ optimized pipeline implementations are a huge asset for our national projects. When we help countries analyze hundreds of thousands of genomes, every performance improvement counts.
DENIZ KURAL, CEO, SEVEN BRIDGES GENOMICS
Intel worked with Seven Bridges to understand the bioinformatic needs of national genomics projects and together build/optimize tools to analyze millions of genomes.
KETAN PARANJAPE, GM INTEL LIFE SCIENCES
More cancer genomes in one place with the US government
The National Institutes of Health’s (NIH) National Cancer Institute (NCI) turned to Seven Bridges to address a critical need in cancer research: how to facilitate research and collaboration on petabyte-scale datasets like The Cancer Genome Atlas(TCGA).
When working with the TCGA, researchers face two problems. The first is data logistics. To download the 2.5PB dataset requires about a month, and to store it over time remains expensive. Second, once they have the data, they need ready access to computational infrastructure to conduct their analyses with it. Previously, the NCI provided funding for multiple grant recipients to download, store, and analyze the data on their own private clusters.
Seven Bridges provided a more efficient solution: bring the TCGA data and tools together on a cloud platform.
This solution enables cancer researchers to access the genomic data and computing tools in an environment that supports rapid discovery. Scientists use the Platform to collaborate on their research from anywhere in the world, bringing their questions to the data. The NCI no longer needs to fund multiple high performance computing clusters. Both benefit from consistent access to data, analysis pipelines, and standard operating procedures.
The project was commissioned by the NIH as a Cancer Genomics Cloud pilot. As part of the contract, Seven Bridges was named the only commercial organization to be a Trusted Partner of the NIH. This means that the US government has authorized us to store, manage, and grant access to Controlled Data from the database for Genotypes and Phenotypes (dbGaP).
Read more about Seven Bridges’ Cancer Genomics Cloud.
Building the future of bioinformatics with the UK government
The government, by way of Genomics England, partnered with Seven Bridges’ algorithmic research and development group in London to commercialize Graph Genome technology. Graph Genomes are the most efficient way to store and analyze population-scale datasets based on millions of individuals. As new genomes are sequenced, the graph yields an increasingly accurate representation of a population’s genetic makeup and an individual’s place within it.
Genomics England will use graph genome technology to analyze data from the 100,000 Genomes project. It will directly aid patients in the British National Health Service and advance genomic research internationally.
Read more about our work on the Graph Genome.
CENTROMERE LABS, BEIJING
In China, home to some of the largest genomics projects in the world, Seven Bridges works with Centromere Labs. In addition to jointly supporting these large-scale genomics analyses, the two companies collaborate on research and development to advance the state of the art in population-scale bioinformatic tool development.
The Seven Bridges Platform
The Seven Bridges Platform is a cloud-based environment for conducting bioinformatic analyses. It is a central hub for teams to store, analyze, and jointly interpret their bioinformatic data. The Platform co-locates analysis pipelines alongside the largest genomic datasets to optimize processing. It allocates storage and compute resources on demand, to meet the needs of ever-growing analyses.The Platform can be incorporated as a layer in other workflows via a flexible Application Programming Interface (API) and can be used to run customized proprietary software via a Docker-based Software Development Kit (SDK).
Understanding the vast amount of genomic data now available demands specialized infrastructure. Our Platform provides a powerful working environment on the cloud, housing pipelines and data together, with elastic scaling of storage and compute resources. We also offer complete local deployments and hybrid cloud solutions.
Learn more about the Seven Bridges Platform.