Blog

We blog about genomics. We also make a platform for open-source analysis of next generation data in the cloud. Hello.

Identifying viral sequences in TCGA data using Kraken and Centrifuge

Image adapted from Kim et al. Genome Res. 26, 1721–1729 (2016). Next-Generation Sequencing has opened up the field of metagenomics. In metagenomic studies, a sample often contains a complex ecosystem of different microorganisms. The key challenge in these experiments is disentangling the identities of unknown species from millions of sequencing reads. Bioinformatic tools for metagenomics are designed to […]

Written by Patrick

Reference bias: Challenges and solutions

Ahead of the Bio-IT World Conference & Expo in Boston this week, we take a look at the role of reference genomes in ensuring accurate genomic analysis. In standard next-generation sequencing analyses, DNA is fragmented and sequenced. The sequenced reads are then aligned to a reference genome for the species. …

Written by Jessica Lau

Simons Genome Diversity Project now available on the Platform and CGC

We’ve just announced the availability of the Simons Genome Diversity Project (SGDP) dataset on our Platform and Cancer Genomics Cloud. In keeping with Seven Bridges’ mission to colocalize data and analysis tools on the cloud, anyone with an internet connection can now explore SGDP’s 35TB of data. One way to …

Written by Patrick

Data democratization advances oncology research

Next week Seven Bridges will be at the Molecular Medicine Tri-Conference in San Francisco, California. Gaurav Kaushik, one of our Scientific Program Managers, will be sharing our work on the Cancer Genomics Cloud (CGC) as part of the conference’s informatics track. Launched publicly in 2016, the Seven Bridges CGC is …

Written by Jessica Lau

Creating a bulletproof workflow

We’ve interviewed some of Seven Bridges’ experienced bioinformaticians to collect their tips and best practices for creating a bulletproof workflow on the Platform. Many bioinformaticians will have experienced the frustration of inexplicably failed analyses, incorrect outputs, or inconsistent results. When dealing with complex tools and gigabytes or even terabytes of …

Written by Marko Marinkovic

Festival of Genomics: Reflecting on graph genomes

Yesterday at Festival of Genomics, London, Seven Bridges CEO Deniz Kural joined a panel discussing implementations of graph genomes, alongside Erik Garrison from the Wellcome Trust Sanger Institute and Andy Yates from EMBL-EBI. Great panel talking about #graph #genomes at #GenomicsFest @erikgarrison @denizkural Andrew Yates @FLGenomics pic.twitter.com/4Cxy2CslvT — Adrian Alexa …

Written by Nick

Implementing precision medicine needs smart connected data

Ahead of the Festival of Genomics, London, we take a look at what needs to happen in order to make biomedical data truly useful for precision medicine. Have you ever tried to show a friend an article or video that you know they would enjoy, but can’t quite find it? …

Written by Patrick

Bioinformatics applications in cancer immunotherapy

An emerging characteristic, or hallmark, of cancer cells is their ability to evade destruction by the immune system. While immune surveillance plays a role in controlling tumorigenesis and tumor progression, cancer cells can in turn disable the immune system by secreting immunosuppressive factors or recruiting immunosuppressive cells. Because of this …

Written by Jessica Lau

The race for a revolutionary new cancer diagnosis tool: The Blood Profiling Atlas in Cancer

A revolutionary approach to cancer diagnosis Liquid biopsy, a new technique for tracking down fragments of tumor DNA in the blood, has the potential to revolutionize how cancer is diagnosed and treated. At next week’s Precision Medicine World Congress, Seven Bridges’ Bruce Press will lead the “Update on the Cancer …

Written by Patrick

We are always engaged in research and development, working to build the future of genomics, science, and health. Let's work together. We'd love to hear about your projects and challenges, so drop us a line. get in touch