We blog about genomics. We also make a platform for open-source analysis of next generation data in the cloud. Hello.

Join us at Beyond the Genome 2014!!

We are looking forward to seeing you at this year’s Beyond the Genome conference at Harvard Medical School from October 8-10! Attending Beyond the Genome is always a highlight for us, but this year we are particularly excited to share news about our efforts supporting cancer genomics research in the cloud. …

Written by brandi

Gibbon genome reveals new insights into mechanisms of primate chromosomal evolution

The gibbon now joins the ranks of nearly 100 mammals with genome assemblies deposited into NCBI’s genome database. – Gracing the cover of today’s issue of Nature, the sequencing and initial analysis of the gibbon genome represents a continuation of efforts, directed by the National Human Genome Research Institute (NHGRI), to sequence …

Written by Devin

Developing an open standard for reproducible genomics pipelines

July was an exciting month for Seven Bridges Software Engineer Boysha Tijanic, who traveled from our Belgrade, Serbia office to give a presentation at ISMB 2014. In his talk, Boysha discussed the importance of transparency and thoroughness when it comes to sharing data and highlighted the complexity of bioinformatic workflows …

Written by carol

De novo transcriptome assembly with RNA-seq data: Using Trinity to examine Caribbean Millepora

Despite the abundance of the hydrocoral genus Millepora, which consists of 19 species distributed in warm waters around the globe, the milleporids have received limited attention in coral reef studies. However, Millepora act as an important component of the reef framework and thus are geologically important. We recently hosted a …

Written by carol

The Global Alliance for Genomics and Health – Meeting Notes

On March 4th, over 200 experts in genomics, healthcare, biomedical research, bioinformatics, ethics, and patient advocacy converged on London. Their destination: The Wellcome Trust at 215 Euston Rd, host of the first meetup of the Global Alliance for Genomics and Health. As a partner of the alliance, we were thrilled …

Written by Edward Hancock

Lior Pachter, biological networks, and the future of science

The scientific community is assessing manners, I think, because so many of us are in a better position to comment on those than on the science. There’s more drama in bioinformatics this past month, as Lior Pachter, with his student Nicolas Bray, published a series of blog posts eviscerating, among …

Written by Nate

Algorithms for Bioinformaticians

One opportunity that comes from working in an infant discipline is that of being able to examine and influence its basic tools. You are more likely to fundamentally improve alignment or assembly than you are to improve the foundations of thermodynamics. And given the state of bioinformatics software, it is …

Written by Nate

Ion Proton RNA-Seq: in search of the best alignment method

Each sequencing technology comes with a unique and unavoidable error profile due to the chemistry, biology, and hardware involved [1,2,3]. If we want avoid analysis artifacts and arrive safely at the biological reality underlying the data, we must to account for these errors during informatic analysis. Recently, researchers have begun tackling …

Written by Kate Blair

World Economic Forum: Technology Pioneers are Boston Strong

With less than a week until Super Bowl XLVIII in New Jersey, we’re taking a look at a different meeting of elites. We’re not talking about Peyton Manning, and we’re certainly not talking about Russell Wilson. Instead, we’re focusing our attention on the World Economic Forum’s Annual Meeting, which took …

Written by carol

We are always engaged in research and development, working to build the future of genomics, science, and health. Let's work together. We'd love to hear about your projects and challenges, so drop us a line. get in touch