Genomics May 23rd, 2017 Identifying viral sequences in TCGA data using Kraken and Centrifuge Image adapted from Kim et al. Genome Res. 26, 1721–1729 (2016). Next-Generation Sequencing has opened up the field of metagenomics. In metagenomic studies, a sample often contains a complex ecosystem of different microorganisms. The key challenge in these experiments is disentangling the identities of unknown species from millions of sequencing reads. Bioinformatic tools for metagenomics are designed to […] Written by Patrick Conferences May 22nd, 2017 Reference bias: Challenges and solutions Ahead of the Bio-IT World Conference & Expo in Boston this week, we take a look at the role of reference genomes in ensuring accurate genomic analysis. In standard next-generation sequencing analyses, DNA is fragmented and sequenced. The sequenced reads are then aligned to a reference genome for the species. … Written by Jessica Lau Graph Genome February 1st, 2017 Festival of Genomics: Reflecting on graph genomes Yesterday at Festival of Genomics, London, Seven Bridges CEO Deniz Kural joined a panel discussing implementations of graph genomes, alongside Erik Garrison from the Wellcome Trust Sanger Institute and Andy Yates from EMBL-EBI. Great panel talking about #graph #genomes at #GenomicsFest @erikgarrison @denizkural Andrew Yates @FLGenomics pic.twitter.com/4Cxy2CslvT — Adrian Alexa … Written by Nick Science January 24th, 2017 Bioinformatics applications in cancer immunotherapy An emerging characteristic, or hallmark, of cancer cells is their ability to evade destruction by the immune system. While immune surveillance plays a role in controlling tumorigenesis and tumor progression, cancer cells can in turn disable the immune system by secreting immunosuppressive factors or recruiting immunosuppressive cells. Because of this … Written by Jessica Lau Blood Profiling January 23rd, 2017 The race for a revolutionary new cancer diagnosis tool: The Blood Profiling Atlas in Cancer A revolutionary approach to cancer diagnosis Liquid biopsy, a new technique for tracking down fragments of tumor DNA in the blood, has the potential to revolutionize how cancer is diagnosed and treated. At next week’s Precision Medicine World Congress, Seven Bridges’ Bruce Press will lead the “Update on the Cancer … Written by Patrick Cancer Genomics Cloud January 12th, 2017 Cancer Cell Line Encyclopedia — Five Key Discoveries Powered by a wave of next generation sequence data from labs and the clinic, oncology is in the midst of a paradigm shift towards personalized medicine. To the modern cancer biologist, the genomic and transcriptomic features of a patient’s tumor have the potential to function as key guideposts for selecting … Written by Patrick Cancer Genomics Cloud August 25th, 2016 Launching the next DREAM Challenge on the Seven Bridges Cancer Genomics Cloud The explosion in biomedical data requires ongoing development of analysis methods and community standards. A proven way of driving innovation is through Challenges—competitions to develop crowdsourced methods to answer specific scientific questions. These challenges offer unique opportunities for academic and commercial communities to advance science by developing precise algorithms and … Written by Nick Conferences April 20th, 2016 Seven Bridges at AACR This week the Seven Bridges team has been participating at the American Association of Cancer Research (AACR) annual meeting, held this year in New Orleans. We’ve been demonstrating the collaborative research benefits of our Cancer Genomics Cloud, and catching up on the latest developments in cancer genomics at AACR. Speaking … Written by Nick Cancer Genomics Cloud April 13th, 2016 Hacking cancer in the cloud Earlier this month, budding hackers from across the US gathered at the Seven Bridges offices in Cambridge, MA. They came to spend the weekend building and applying tools for cancer research using the Cancer Genomics Cloud (CGC). The CGC brings together data from The Cancer Genome Atlas (TCGA) and other … Written by Nick Posts navigation 1 2 3 4 5
