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Unveiling the Power of Connected Data: A Deep Dive into the Velsera Seven Bridges Platform

In the ever-evolving landscape of scientific research, the key to discovery lies in the data. What could you do with over 14 petabytes of multimodal data spanning a million subjects and multiple model organisms?   Welcome to the Velsera Seven Bridges Core Platform, where connectivity, collaboration and analysis meet discovery.   The …

Written by Michele Mattioni, PhD, Director of Interoperability & Standards at Velsera, Jared Rozowsky, PhD, Technical Scientific Program Manager at Velsera, Cera Fisher, PhD, Community Engagement Manager at Velsera

Exploring the Science Behind Neoantigen Discovery from Mutations to Proteins

Contributors: Julie Gil, Ph.D., Sarah Kleinstein, Ph.D., Cera Fisher, Ph.D., Dennis Dean Ph.D., and Kristina Clemens Ph.D. During the COVID-19 pandemic, many of us gained first-hand experience of the efficacy of mRNA vaccines. Twenty years of dedicated research in the general application of mRNA vaccines fueled the rapid delivery of …

Written by Jeffrey Brabec, PhD, Scientific Partner at Velsera

Unlocking BioCompute Objects: Velsera’s Commitment to Interoperability and Regulatory Excellence

At Velsera, we’re passionate about paving the way for the future of bioinformatics and regulatory excellence. We collaborated with the BioCompute Object (BCO) community to develop the BCO standard for communicating complex Next Generation Sequencing (NGS) workflows for regulatory review and developed an award-winning app that generates BCOs from complex …

Written by Biran Lassiter

Making the Impossible, Possible: Harnessing the Cloud to Uncover Rare Somatic Variations in Cancer Patients

Limited by computational resources, the Khiabanian lab at Rutgers needed a breakthrough.   The lab was looking at rare changes in blood cells linked to a condition called CHIP (clonal hematopoiesis of indeterminate potential). This condition has been associated with certain types of treatment-induced cancers as well as resistance to cancer …

Written by Cera Fisher

Advancing Multi-omics Analysis by Co-localizing Data, Workflows, and Computation

The power – and increasing cost-effectiveness – of ‘omic technologies has provided groundbreaking insights into the underpinnings of biology and has revolutionized the process of target and drug discovery.  A method like transcriptomics can provide a snapshot of genetic activity under certain conditions while proteomics can tell us which of …

Written by Jeffrey Brabec, PhD

Unlocking Insights: Accelerating Precision Medicine with Multi-Omics and Collaborative Platforms

I have long been fascinated with data’s power to drive new insights, including developing a deeper understanding of human physiology/pathophysiology, informing decision-making, and guiding the development of new treatment options. Often novel complex analysis methods are linked to specialized visualizations to drive the development and use of these insights. My …

Written by Dennis A. Dean, II, PhD

Unleashing the Power of Multi-Modal Data: Pioneering Precision Medicine in the Digital Age

In recent years, precision medicine has witnessed remarkable progress, thanks to multi-omics and multi-modal data integration.[1,2] This holds immense potential for advancing healthcare in various domains, such as risk target identification, trial design, diagnostic analytics, population health analysis, lab automation, and clinical decision support[3,4,5]. Whether you are part of industry, …

Written by Dennis A. Dean, II, PhD

Advancing Alzheimer’s Treatment and Inclusive Research

This month represented an important step forward in the treatment of Alzheimer’s disease with Eli Lilly announcing the successful results of their phase III clinical trials for their monocolonal antibody (mAB) donanemab. In addition to decreasing the overall amyloid burden, patients on the drug showed slowed disease progression and sustained …

Written by Jeffrey Brabec, Nick Legendre

Assessing State of the Art Bioinformatics

The Oxford English Dictionary defines bioinformatics as “the science of information and information flow in biological systems, especially of the use of computational methods in genetics and genomics.” In common vernacular, it is often defined as the use of statistical and computing methods to solve or better understand complex biological …

Written by Vladimir Kovacevic

We are always engaged in research and development, working to build the future of genomics, science, and health. Let's work together. We'd love to hear about your projects and challenges, so drop us a line.

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