Release notes

March 26th, 2018

Smart Variant Filtering

The variant filtering process consists of selecting highly confident variants and removing the ones that are falsely called. This process used to be mostly left out from deeper testing in secondary genomic DNA analyses, even though it can boost precision of variant calls significantly. After developing graph genome alignment tool and reassembly variant caller, we are now launching the Smart Variant Filtering tool used for filtering germline variants.

Smart Variant Filtering (SVF) uses machine learning algorithms trained on features from the existing Genome In A Bottle (GIAB) variant-called samples (HG001-HG005) to perform variant filtering (classification). The comparison results obtained during deep, three-stage testing demonstrate that it outperforms the solutions currently used within most secondary DNA analyses. Smart Variant Filtering increases the precision of called SNVs (removes false positives) by up to 0.2% points while keeping the overall f-score higher by 0.12-0.27% points than in existing solutions.

Learn more about the Smart Variant Filtering public project from our documentation.

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March 19th, 2018

TLS 1.0 and TLS 1.1 no longer supported

We have removed support for TLS 1.0 and TLS 1.1 protocols. The only supported protocol on our Platform and API is TLS 1.2. If you are using a client that does not support TLS 1.2, please perform an upgrade to continue using the Seven Bridges Platform.

More about the TLS protocol

The TLS (Transport Layer Security) protocol is a cryptographic protocol that provides communications security in a computer network. It’s a successor of the SSL (Secure Sockets Layer) protocol that is now prohibited from use by IETF. TLS provides both confidentiality and data integrity in transit between two communicating computers. TLS version 1.2 is a modern version of this protocol that enables highest possible communication security between your application/browser and our Platform/API. The deprecated versions, TLS 1.0 and TLS 1.1, have a number of known weaknesses, and it is in the best interest of our users to use the up-to-date version.

Supported clients

If you are using Internet Explorer, make sure that you upgrade your browser to version 11 or later. If you are using an up-to-date version of Chrome, Firefox or Safari – you are all set.

If you have any follow-up questions, feel free to contact the Seven Bridges Support Team.

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March 5th, 2018

ImprovementsFile page improvements

Now, you can view html, b64html, RNA vis index, ingenuity report, bench SQLite, PDF, GIF, JPEG, SVG, PNG, and ipynb files from the File page without downloading the file. Please be aware when opening files for preview or when downloading files that they are from a trusted source.

Note that file metadata is now collapsed by default. Click on the info icon in the top right to view file metadata.
Please contact support@sbgenomics.com for any file-related issues.

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February 26th, 2018

NewQuery with search terms

We’ve improved querying datasets via the Data Browser. After selecting one or more datasets, you can use search terms to start your query. Terms will autocomplete as you type and suggest Keywords, Related queries, and Saved and example queries. Select a query from Related queries or Saved and examples. Or, enter more keywords and hit enter to choose a pre-built query from the Results page. This intuitive feature enables users to familiarize themselves with the Data Browser and lowers the learning curve to query building.

Learn more from our documentation.

 

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February 9th, 2018

NewSupported instances update

We now support the use of new generation AWS EC2 Compute Optimized instances (C5) and General Purpose instances (M5) in task executions and Data Cruncher analyses on the Seven Bridges Platform. Note that these instances are not available on eu.sbgenomics.com.

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December 22nd, 2017

ImprovementsBatch improvements

We’ve improved the batching functionality on the visual interface. In addition to the existing batching methods, you can now toggle batching on and off for any workflow on the DRAFT task page. You can also set batching criteria by any metadata, as was previously available on the API.

Learn more from our documentation.

ImprovementsData Cruncher – Suspend time

You can now set the period of inactivity after which the instance is stopped automatically and the analysis is saved.

Learn more from our documentation.

V2 Transition

On January 31, 2018, Seven Bridges will deprecate legacy projects and features on the Seven Bridges Platform. Apps, tasks, and data within your legacy projects will remain accessible. Port these to Version 2 projects to conduct further analyses.

Learn more from our post.

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November 17th, 2017

ImprovementsPhenotype visualization improvement for Sonar

We’ve improved phenotype visualizations in the Sonar Playground. Use the scatterplot to visualize up to three dimensions of your query and observe trends or refine your original query. Note that this visualization is currently available only for single queries. Learn more about scatterplots for your queries.

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November 3rd, 2017

Sign-on (Enterprise)

The Seven Bridges Platform now supports integration with third-party authentication services that are SAML2.0 compatible. We can quickly setup external authentication on a division level as requested by the client.

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October 27th, 2017

ImprovementsAmazon KMS support for Volumes

You can now use Amazon KMS with your Amazon S3 volume. Simply provide your KMS ID when configuring your volume for the Platform. Learn more from Amazon’s documentation about using a KMS ID.

ImprovementsUpdating Help functionality

Use the Help icon on the bottom of each page to access customer support, send feedback, and find contextual supporting documentation all in the same place.

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We are always engaged in research and development, working to build the future of genomics, science, and health. Let's work together. We'd love to hear about your projects and challenges, so drop us a line.

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