ImprovementsFolder options for FTP/HTTP(S) import
When importing data from an FTP or HTTP(S) server to the Platform, you are now able to import an entire folder structure in the exact same form as it appears on its source server, or choose to “flatten” the structure and import the files only. Also, the Platform now provides a selection of naming conflict resolution options for FTP/HTTP(S) imports. If an item that is being imported has the same name as an item already present at the target location, you can select whether to skip importing the item, overwrite the existing one or auto-rename the one that is being imported. Learn more.
ImprovementsR client updates
The sevenbridges-r API client has been updated with several sets of API calls. Precisely, the new additions include Folders, Enterprise, Bulk, Actions and Markers (Advance Access) APIs. Moreover, the R client now also supports setting execution hints per task run when drafting new tasks.
In order to improve your experience with our R client, we have optimized package installation and loading time. Also, the documentation website for the R client has been updated with new styling and improved text readability. To download the latest version and get more information, please visit the Releases page on GitHub and read the documentation.
NewNew file search option
When searching for files within a project, now you have the option to search within the current folder only, without including subfolders and their content in the search. Until now, the default behavior was that the current folder (or project root) and all of its subfolders got included in the search, with the Path column being shown in the search results. This remains the default behavior, but now there is an additional option to search through items from the current path (project root or folder) only, without searching through subfolders.
One of the two file search options can be selected by clicking the search icon within the file search field. Learn more.
ImprovementsOpen apps for editing in web editors more easily
The option to edit apps in the tool or workflow editor on the Platform is now more accessible through the visual interface. When the Edit option is clicked for an app, all sbg:draft-2 apps will be opened in the corresponding web editor by default. However, you still have the option to edit sbg:draft-2 apps in Rabix Composer, our standalone app editor from the Rabix toolkit. For now, Rabix Composer also remains the only editor for CWL 1.0 apps.
Recently published apps
Control-FREEC analyzes copy-number alterations in exome and whole-genome DNA sequencing. This tool computes, normalizes and segments copy number and beta allele frequency (BAF) profiles, then calls copy number alterations and LOH.
NewDefine compute resources per task run (API)
When creating a task via the API, you are now able to set instance type (top level) and maximum number of parallel instances for your execution without the need to create a new version of the app.
The following API calls have been modified to allow you to set or retrieve instance information for a specific task:
Support for compute resource settings per task run will soon be available on our visual interface as well.
ImprovementsFolders become a standard API feature
Folders are no longer in the Advance Access stage and are available as a standard feature on the API. Apart from not having to use the X-SBG-Advance-Access header for API calls related to folders, you are now also able to specify the destination folder within a project when uploading a file. Find out more in the Files, folders and metadata section of our API documentation.
Improvements Activate spot instances on project creation
When creating a new project through the visual interface, you are now able to set your preference for Spot instance usage in the Create a project dialog. This setting can later be changed from the project settings page, or overridden per task on the draft task page. Learn more about Spot Instances on our Platform.
ImprovementsData Cruncher – JupyterLab Beta
We have also made more improvements in order to reduce analysis initialization time. It shouldn’t take more than four minutes to spin up your Data Cruncher analysis, regardless of the chosen compute resources.
Updates to the TCGA, TARGET, and CCLE datasets
As part of Seven Bridges’ ongoing partnership with the National Cancer Institute (NCI), authorized researchers can access valuable public datasets generated by the TCGA, TARGET, and CCLE initiatives through the Seven Bridges Platform, and Seven Bridges collaborates with the NCI Genomic Data Commons (GDC) on an ongoing basis to ensure alignment between the datasets available through the GDC and our Platform. In keeping with this, updated versions of the TCGA, TARGET, and CCLE datasets have been released on the Seven Bridges Platform. As of July 10, the legacy TCGA and CCLE datasets available through our Platform are fully aligned with those in the GDC Legacy Archive, and the TCGA GRCh38 and TARGET GRCh38 datasets are fully aligned with GDC Data Release 11.0. However, please note that this update is not currently available if you are using the Seven Bridges Platform on AWS EU as the cloud infrastructure provider.
As a result of these dataset improvements, some users who previously copied files from these datasets to their projects will no longer be able to access a subset of these files. In advance of the release of these new dataset versions, Seven Bridges contacted the owners of all affected projects. The users who were not contacted by Seven Bridges or by the owner of projects on which they collaborate can expect access to all TCGA, TARGET, and CCLE files in their current projects to continue without interruption.
ImprovementsSet null or empty values for app settings
When defining app settings prior to execution, you are now able to set null or empty values for the available inputs. This is possible using the two new buttons placed next to the inputs under the Define App Settings tab.
The Set null option is available both for simple inputs (such as strings or numeric values) and complex ones (such as arrays, records or maps).
Set empty is available as a button only for complex inputs (arrays, records and maps). For most of the simple app parameters, such as strings, empty value is set by simply removing the value from the input field and leaving the field blank.
We have also introduced support for displaying certain more complex input types, such as arrays of records, that are now also available through the visual interface.
NewVariant Browser (BETA)
Variant Browser is under active development with features being added successively. For any suggestions or bug reports, please contact our support team at email@example.com.
Variant Browser is an application for genome analysis and interpretation that will allow researchers and clinicians to quickly annotate and accurately prioritize variants and genes involved in a disease. Variant Browser bridges the gap between sequencing/raw data management and clinical management, providing robust genome interpretation to expedite diagnosis and accelerate the understanding of the genetic basis of disease, drug response, and health.
During the BETA stage, you are able to interpret demo VCF files which are readily available inside the app. The available options include filtering with configurable filtering criteria, directly opening the Genome Browser at the position of the selected variant and displaying general statistics for the currently applied filters. In case you want to interpret your own VCF files please contact us at firstname.lastname@example.org.
Future development will include an integrated flow for annotation and interpretation of VCF files using the Variant Browser, with annotated files provided by annotation apps on the Seven Bridges Platform (such as VEP annotation workflow or SnpEff), or uploaded by the users. Additionally, there will be more detailed and elaborate filtering options, along with more comprehensive display options for relevant analysis information.
Try the Variant Browser right now by accessing it in your project’s Interactive Analysis section and read more about it in the documentation.
Variant Browser resources
Several resources that will be used for creation of sqlite databases to be browsed further with Variant Browser are already available on the Seven Bridges Platform. Those are annotation workflows based on VEP (Variant Effect Predictor) and SnpEff. Workflows for annotation and conversion of a single VCF file to an sqlite database are: VEP annotation & DB conversion and SnpEff annotation & DB conversion, as well as Trios: SnpEff annotation & DB conversion or Trios: VEP annotation & DB conversion in case of Trios analysis. The workflows are available in the Variant Browser public project.