We blog about genomics. We also make a platform for open-source analysis of next generation data in the cloud. Hello.

Advancing Alzheimer’s Treatment and Inclusive Research

This month represented an important step forward in the treatment of Alzheimer’s disease with Eli Lilly announcing the successful results of their phase III clinical trials for their monocolonal antibody (mAB) donanemab. In addition to decreasing the overall amyloid burden, patients on the drug showed slowed disease progression and sustained …

Written by Jeffrey Brabec, Nick Legendre

Highly Customizable Multi-sample Single Cell RNA-Seq Pipeline on the CGC

“To study human biology, we must know our cells!”  – this is a quote from a paper published a couple of years back [1], where authors of the paper presented early-stage ideas and proofs-of-concept behind The Human Cell Atlas Project, an international collaborative effort aiming to define all human cell …

Written by Nevena Vukojičić, Aleksandar Daničić, Cera Fisher

Meeting the NIH Data Management and Sharing (DMS) policy requirements with community-focused cloud platforms

The Velsera suite of NIH-funded platforms including Cancer Genomics Cloud (CGC), BioData Catalyst Powered by Seven Bridges (BDC-Seven Bridges) and CAVATICA provide secure, interoperable and scalable biomedical data analysis solutions for governments, universities, institutions, and research consortia. The platforms enable a shared research environment that empower the users to bring …

Written by Surya Saha, Michele Mattioni, Jared Rozowsky, Zélia Worman

Manifest-based DRS import: A practical solution for cross-dataset analysis to empower translational research

A key challenge in data discovery is the coordination and assembly of datasets spanning multiple from across Data Coordination Centers on a cloud compute platform in a way that is both easy to use and meaningful. To meet this challenge, we have implemented a GA4GH Data Repository Service (DRS) manifest-based …

Written by Surya Saha

Visualizing multiomics data with the OmicCircos app on CGC

Seven Bridges (Velsera) is excited to announce the launch of the OmicCircos R shiny app on the Cancer Genomics Cloud (CGC) platform. The OmicCircos app has been developed in collaboration with the Dr. Daoud Meerzaman laboratory at the NCI, developers of the R Bioconductor OmicCircos package. The R shiny application …

Written by Divya Sain

Looking for an interactive variant association visualizer that produces publication quality plots?

GWAS results can be difficult to interpret, especially for those without a scripting background. Genome Wide Association Studies (GWAS) has revealed loci associated with common human genetic diseases such as coronary artery disease in genetically diverse populations.Single variant association tests are used in testing for association between genetic variants and …

Written by Aarthi Krishnan

We are excited to announce the release of dbGaP Submission Form Suite!

This is a new RShiny App on the Cancer Genomics Cloud (CGC) that streamlines the way a CGC user can submit their data to dbGAP! The dbGaP Submission Form Suite app allows a user to easily import, map and prepare their data for import into the database of Genotypes and …

Written by Biran Lassiter

We are always engaged in research and development, working to build the future of genomics, science, and health. Let's work together. We'd love to hear about your projects and challenges, so drop us a line.

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