Science October 22nd, 2013 Better sequences (and fewer homopolymer errors) for Ion Torrent The short read files that Ion Torrent’s sequencing machines give us still contain many homopolymer errors: errors in the number of bases called when a single nucleotide occurs more than once in sequence. This makes alignment harder and drowns real indels in a sea of noise. These homopolymer errors arise … Written by Nate Science February 5th, 2013 RNA-Seq: The first wave of papers A flurry of papers in May of 2008 introduced the world to RNA-Seq. This new technology provided a higher resolution picture of transcription than was possible ever before. Nearly five years on, we look back at the publications that upset the microarray industry and sent tweed-clad professors scrambling for the … Written by Kate Blair